Possible contributions of lipoproteins and cholesterol to the pathogenesis of diabetes mellitus type 2.

von Eckardstein, Arnold; Sibler, Rahel A
Current opinion in lipidology; 2011 Feb;22(1):26-32. PMID: 21102330
Institute of Clinical Chemistry, University and University Hospital Zurich, Switzerland.


Low HDL cholesterol and hypertriglyceridemia as well as lowering of LDL cholesterol with statins increase the risk of T2DM. We discuss the recent findings on the effects of lipoproteins and cholesterol on the function and survival of pancreatic β-cells as well as on obesity and insulin sensitivity of muscle and liver.