Pioglitazone for diabetes prevention in impaired glucose tolerance.

DeFronzo, Ralph A; Tripathy, Devjit; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Clement, Stephen C; Henry, Robert R; Hodis, Howard N; Kitabchi, Abbas E; Mack, Wendy J; Mudaliar, Sunder; Ratner, Robert E; Williams, Ken; Stentz,
The New England journal of medicine; 2011 Mar 24;364(12):1104-15. PMID: 21428766
Texas Diabetes Institute and University of Texas Health Science Center, San Antonio, TX 78229, USA.


Impaired glucose tolerance is associated with increased rates of cardiovascular disease and conversion to type 2 diabetes mellitus. Interventions that may prevent or delay such occurrences are of great clinical importance.