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Pioglitazone for diabetes prevention in impaired glucose tolerance.

DeFronzo, Ralph A; Tripathy, Devjit; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Clement, Stephen C; Henry, Robert R; Hodis, Howard N; Kitabchi, Abbas E; Mack, Wendy J; Mudaliar, Sunder; Ratner, Robert E; Williams, Ken; Stentz,
The New England journal of medicine; 2011 Mar 24;364(12):1104-15. PMID: 21428766
Texas Diabetes Institute and University of Texas Health Science Center, San Antonio, TX 78229, USA. albarado@uthscsa.edu
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Abstract

Impaired glucose tolerance is associated with increased rates of cardiovascular disease and conversion to type 2 diabetes mellitus. Interventions that may prevent or delay such occurrences are of great clinical importance.