Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled study.

Haak, Thomas; Meinicke, T; Jones, R; Weber, S; von Eynatten, M; Woerle, H-J
Diabetes, obesity & metabolism; 2012 Jun;14(6):565-74. PMID: 22356132
Diabetes Center Mergentheim, Bad Mergentheim, Germany.


To evaluate the efficacy and safety of initial combination therapy with linagliptin plus metformin versus linagliptin or metformin monotherapy in patients with type 2 diabetes.