Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.

Wang, Q; Brubaker, P L
Diabetologia; 2002 Sep;45(9):1263-73. PMID: 12242459
Department of Physiology, University of Toronto, Toronto, Ontario, Canada.


Glucagon-like peptide-1 ameliorates the symptoms of diabetes through stimulation of insulin secretion and enhancement of beta-cell mass. We have therefore investigated the effects of glucagon-like peptide-1 on the development of diabetes, using db/db mice as a model of Type II diabetes.