Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials.

Baigent, Colin; Blackwell, Lisa; Collins, Rory; Emberson, Jonathan; Godwin, Jon; Peto, Richard; Buring, Julie; Hennekens, Charles; Kearney, Patricia; Meade, Tom; Patrono, Carlo; Roncaglioni, Maria Carla; Zanchetti, Alberto
Lancet; 2009 May 30;373(9678):1849-60. PMID: 19482214
CTSU, Oxford University, Oxford, UK.


Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed the benefits and risks in primary prevention.