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Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus.

Kooy, Adriaan; de Jager, Jolien; Lehert, Philippe; Bets, Daniël; Wulffelé, Michiel G; Donker, Ab J M; Stehouwer, Coen D A
Archives of internal medicine; 2009 Mar 23;169(6):616-25. PMID: 19307526
Department of Internal Medicine and Bethesda Diabetes Research Center, RA Hoogeveen, the Netherlands. kooy.a@bethesda.nl
Category: 
General Reviews
Links: 
PubMed Article
Journal Article

Abstract

We investigated whether metformin hydrochloride has sustained beneficial metabolic and (cardio) vascular effects in patients with type 2 diabetes mellitus (DM2).