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Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.

Weng, Jianping; Li, Yanbing; Xu, Wen; Shi, Lixin; Zhang, Qiao; Zhu, Dalong; Hu, Yun; Zhou, Zhiguang; Yan, Xiang; Tian, Haoming; Ran, Xingwu; Luo, Zuojie; Xian, Jing; Yan, Li; Li, Fangping; Zeng, Longyi; Chen, Yanming; Yang, Liyong; Yan, Sunjie; Liu, Juan; Li, Ming; Fu, Zuzhi; Cheng, Hua

Lancet; 2008 May 24;371(9626):1753-60. PMID: 18502299;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention).

Gerstein, Hertzel; Yusuf, Salim; Riddle, Matthew C; Ryden, Lars; Bosch, Jackie

American heart journal; 2008 Jan;155(1):26-32, 32.e1-6. PMID: 18082485;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy, metformin
Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function.

Li, Yanbing; Xu, Wen; Liao, Zhihong; Yao, Bin; Chen, Xiahua; Huang, Zhimin; Hu, Guoliang; Weng, JianPing

Diabetes care; 2004 Nov;27(11):2597-602. PMID: 15504992;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy

Closed-loop insulin delivery: from bench to clinical practice

Roman Hovorka

Nature Reviews Endocrinology

Category: Interventions / Insulin;

Tags: insulin therapy
Randomized, open-label, parallel-group evaluations of basal-bolus therapy versus insulin lispro premixed therapy in patients with type 2 diabetes mellitus failing to achieve control with starter insulin treatment and continuing oral antihyperglycemic drug

Miser, William F; Arakaki, Richard; Jiang, Honghua; Scism-Bacon, Jamie; Anderson, Pamela W; Fahrbach, Jessie L

Clinical therapeutics; 2010 May;32(5):896-908. PMID: 20685497;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Prevention of nocturnal hypoglycemia using predictive alarm algorithms and insulin pump suspension.

Buckingham, Bruce; Chase, H Peter; Dassau, Eyal; Cobry, Erin; Clinton, Paula; Gage, Victoria; Caswell, Kimberly; Wilkinson, John; Cameron, Fraser; Lee, Hyunjin; Bequette, B Wayne; Doyle, Francis J

Diabetes care; 2010 May;33(5):1013-7. PMID: 20200307;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial.

Hovorka, Roman; Allen, Janet M; Elleri, Daniela; Chassin, Ludovic J; Harris, Julie; Xing, Dongyuan; Kollman, Craig; Hovorka, Tomas; Larsen, Anne Mette F; Nodale, Marianna; De Palma, Alessandra; Wilinska, Malgorzata E; Acerini, Carlo L; Dunger, David B

Lancet; 2010 Feb 27;375(9716):743-51. PMID: 20138357;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Three-year efficacy of complex insulin regimens in type 2 diabetes.

Holman, Rury R; Farmer, Andrew J; Davies, Melanie J; Levy, Jonathan C; Darbyshire, Julie L; Keenan, Joanne F; Paul, Sanjoy K

The New England journal of medicine; 2009 Oct 29;361(18):1736-47. PMID: 19850703;

Category: Interventions / Insulin;
Does diabetes therapy influence the risk of cancer?

Smith, U; Gale, E A M

Diabetologia; 2009 Sep;52(9):1699-708. PMID: 19597799;

Category: Interventions / Insulin;
Once-daily insulin detemir is comparable to once-daily insulin glargine in providing glycaemic control over 24 h in patients with type 2 diabetes: a double-blind, randomized, crossover study.

King, A B

Diabetes, obesity & metabolism; 2009 Jan;11(1):69-71. PMID: 19120433;

Category: Interventions / Insulin;
Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.

Weng, Jianping; Li, Yanbing; Xu, Wen; Shi, Lixin; Zhang, Qiao; Zhu, Dalong; Hu, Yun; Zhou, Zhiguang; Yan, Xiang; Tian, Haoming; Ran, Xingwu; Luo, Zuojie; Xian, Jing; Yan, Li; Li, Fangping; Zeng, Longyi; Chen, Yanming; Yang, Liyong; Yan, Sunjie; Liu, Juan; Li, Ming; Fu, Zuzhi; Cheng, Hua

Lancet; 2008 May 24;371(9626):1753-60. PMID: 18502299;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Comparison of biphasic insulin aspart 30 given three times daily or twice daily in combination with metformin versus oral antidiabetic drugs alone in patients with poorly controlled type 2 diabetes: a 16-week, randomized, open-label, parallel-group trial

Ushakova, Olga; Sokolovskaya, Vera; Morozova, Alla; Valeeva, Farida; Zanozina, Olga; Sazonova, Olga; Zhadanova, Elena; Starceva, Maria; Kazakova, Elena; Saifullina, Marina; Shapiro, Irina; Tarasov, Alexander; Al-Tayar, Bassam; Starkova, Ninella

Clinical therapeutics; 2007 Nov;29(11):2374-84. PMID: 18158078;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention).

Gerstein, Hertzel; Yusuf, Salim; Riddle, Matthew C; Ryden, Lars; Bosch, Jackie

American heart journal; 2008 Jan;155(1):26-32, 32.e1-6. PMID: 18082485;

Category: Interventions / Insulin;

Tags: glycemic control, insulin therapy, metformin

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Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.

Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention).

Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function.

Closed-loop insulin delivery: from bench to clinical practice

Randomized, open-label, parallel-group evaluations of basal-bolus therapy versus insulin lispro premixed therapy in patients with type 2 diabetes mellitus failing to achieve control with starter insulin treatment and continuing oral antihyperglycemic drug

Prevention of nocturnal hypoglycemia using predictive alarm algorithms and insulin pump suspension.

Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial.

Three-year efficacy of complex insulin regimens in type 2 diabetes.

Does diabetes therapy influence the risk of cancer?

Once-daily insulin detemir is comparable to once-daily insulin glargine in providing glycaemic control over 24 h in patients with type 2 diabetes: a double-blind, randomized, crossover study.

Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.

Comparison of biphasic insulin aspart 30 given three times daily or twice daily in combination with metformin versus oral antidiabetic drugs alone in patients with poorly controlled type 2 diabetes: a 16-week, randomized, open-label, parallel-group trial

Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: the ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention).