beta cell pathophysiology

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Topics include original Beta Cells in Diabetes content, as well as expert-selected resources chosen by our Editorial Board.

Improving Diabetes Care in Practice: findings from the TRANSLATE trial.

Peterson, Kevin A; Radosevich, David M; O'Connor, Patrick J; Nyman, John A; Prineas, Ronald J; Smith, Steven A; Arneson, Thomas J; Corbett, Victor A; Weinhandl, Joyce C; Lange, Carol J; Hannan, Peter J
Diabetes care; 2008 Dec;31(12):2238-43. PMID: 18809622;
Category: General Reviews;

MODY: An Increasingly Important and Often Overlooked Form of Diabetes

 Dr. Leahy and Dr. Hirsch provide a great introduction to the very latest info on MODY!  Dr. Leahy’s frank discussion of practical diagnostic considerations in patients with hyperglycemia who do not easily fit into the classification of type 1 or type 2 diabetes provides a refreshing look at how we practice today and a peek at how we may practice in the future.

Obesity and Type 2 Diabetes: What is Similar and What is Different

Medical experts from around the world gathered recently for the 47th European Association for the Study of Diabetes (EASD) annual meeting in Lisbon, Portugal to review the latest research findings and trends in diabetes and metabolic disease.

Metabolic implications of body fat distribution.

Björntorp, P
Diabetes care; 1991 Dec;14(12):1132-43. PMID: 1773700;
Category: General Reviews;

Obesity and type 2 diabetes: what can be unified and what needs to be individualized?

Eckel, Robert H; Kahn, Steven E; Ferrannini, Ele; Goldfine, Allison B; Nathan, David M; Schwartz, Michael W; Smith, Robert J; Smith, Steven R
Diabetes care; 2011 Jun;34(6):1424-30. PMID: 21602431;
Category: General Reviews;

Obesity and type 2 diabetes: what can be unified and what needs to be individualized?

Eckel, Robert H; Kahn, Steven E; Ferrannini, Ele; Goldfine, Allison B; Nathan, David M; Schwartz, Michael W; Smith, Robert J; Smith, Steven R
The Journal of clinical endocrinology and metabolism; 2011 Jun;96(6):1654-63. PMID: 21602457;
Category: General Reviews;

Urinary C-peptide creatinine ratio is a practical outpatient tool for identifying hepatocyte nuclear factor 1-{alpha}/hepatocyte nuclear factor 4-{alpha} maturity-onset diabetes of the young from long-duration type 1 diabetes.

Besser, Rachel E J; Shepherd, Maggie H; McDonald, Timothy J; Shields, Beverley M; Knight, Bridget A; Ellard, Sian; Hattersley, Andrew T
Diabetes care; 2011 Feb;34(2):286-91. PMID: 21270186;
Category: Interventions;

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

Morino, Katsutaro; Petersen, Kitt Falk; Dufour, Sylvie; Befroy, Douglas; Frattini, Jared; Shatzkes, Nadine; Neschen, Susanne; White, Morris F; Bilz, Stefan; Sono, Saki; Pypaert, Marc; Shulman, Gerald I
The Journal of clinical investigation; 2005 Dec;115(12):3587-93. PMID: 16284649;
Category: General Reviews;

Case 5: Graduate Student with Atypical Symptoms

A 25-year-old graduate student originally presented to you with symptoms of a UTI. An urinanalysis showed signs of infection, as well as glycosuria.

Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis.

Preiss, David; Seshasai, Sreenivasa Rao Kondapally; Welsh, Paul; Murphy, Sabina A; Ho, Jennifer E; Waters, David D; DeMicco, David A; Barter, Philip; Cannon, Christopher P; Sabatine, Marc S; Braunwald, Eugene; Kastelein, John J P; de Lemos, James A; Blazing, Michael A; Pedersen, Terje R; Tikkanen, Matti J; Sattar, Naveed; Ray, Kausik K
JAMA : the journal of the American Medical Association; 2011 Jun 22;305(24):2556-64. PMID: 21693744;
Category: General Reviews;
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